Septerna Inc (SEPN) is a good investment, but the stock may be undervalued

Patricia Turner

While Septerna Inc has underperformed by -1.66%, investors are advised to look at stock chart patterns for technical insight. Within its last year performance, SEPN fell by -10.76%, with highs and lows ranging from $30.50 to $4.17, whereas the simple moving average jumped by 61.57% in the last 200 days.

On December 19, 2025, Raymond James started tracking Septerna Inc (NASDAQ: SEPN) recommending Strong Buy. A report published by Truist on December 15, 2025, Initiated its previous ‘Buy’ rating for SEPN. H.C. Wainwright Initiated an Buy rating on June 23, 2025, and assigned a price target of $26. Wells Fargo February 18, 2025d its ‘Overweight’ rating to ‘Equal Weight’ for SEPN, as published in its report on February 18, 2025. Wells Fargo’s report from November 19, 2024 suggests a price prediction of $43 for SEPN shares, giving the stock a ‘Overweight’ rating. TD Cowen also rated the stock as ‘Buy’.

Analysis of Septerna Inc (SEPN)

Further, the quarter-over-quarter increase in sales is 12113.07%, showing a positive trend in the upcoming months.

Septerna Inc’s future performance can be predicted by a variety of well-rounded types of analysis and research, with equity being one of the most crucial ones. The goal here is to ensure that your current return on equity of -22.38% is sufficient for you to turn a profit off your investment. Taking into account the quick ratio of the company, currently set at 6.53, you can see that the company can cover any debts it may have, which can easily be seen in the annual report of the company.

For any stock, average volume can be an extremely valuable indicator of volatility, and SEPN is registering an average volume of 320.76K. On a monthly basis, the volatility of the stock is set at 5.47%, whereas on a weekly basis, it is put at 5.03%, with a loss of -7.13% over the past seven days. Furthermore, long-term investors anticipate a median target price of $33.71, showing growth from the present price of $24.88, which can serve as yet another indication of whether SEPN is worth investing in or should be passed over.

How Do You Analyze Septerna Inc Shares?

Besides checking the fundamentals, you should also know how many employees own shares in the company. This is because the values should be in line with investors’ expectations. As such, the current holdings of company stock inside the company are set at 39.81%. This can enable you to see the extent to which executives own the company’s stock. As opposed to executive stock, institutional ownership accounts for 63.27% of the company’s shares, contributing to an indication of company value, since large shareholders may signify strength within the organization.

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